CRISPR-mediated direct mutation of cancer genes in the mouse liver.
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T
Nature. 2014 Aug 6. doi: 10.1038/nature13589. PubMed Article
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T
Nature. 2014 Aug 6. doi: 10.1038/nature13589. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 59909 | pX330 Pten | pX330 backbone expressing sgRNA targeting Pten to edit mouse Pten. Expresses Cas9 from CBh promoter |
| 59910 | pX330 p53 | pX330 backbone expressing sgRNA targeting p53 to edit mouse p53. Expresses Cas9 from CBh promoter |
| 59911 | pX330 Ctnnb1.1 | pX330 backbone expressing sgRNA targeting Ctnnb1 to edit mouse beta-Catenin. Expresses Cas9 from CBh promoter |
| 59912 | pX330 Ctnnb1.2 | pX330 backbone expressing sgRNA targeting Ctnnb1 to edit mouse beta-Catenin. Expresses Cas9 from CBh promoter |