RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, Teruya-Feldstein J, Kelliher MA, Speleman F, Porco JA Jr, Pelletier J, Ratsch G, Wendel HG
Nature. 2014 Sep 4;513(7516):65-70. doi: 10.1038/nature13485. Epub 2014 Jul 27.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 70039 | PGL4-4X TE Down (GQs) Renilla | Plasmid for testing 5’UTR TE Down (G-quadruplex) folding elements |
| 70040 | PGL4-4X Mut Renilla | Control plasmid for testing 5'UTR folding elements |
| 70042 | MIG-eIF4A1 P159E | Expression of eIF4A1 P159E mutant construct in mammalian cells. |
| 70043 | MIG-eIF4A1 F163L | Expression of eIF4A1 F163L mutant in mammalian cells |
| 70044 | MIG-eIF4A1 Q195E | Expression of eIF4A1 Q195E mutant in mammalian cells |