Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

KRAS and YAP1 Converge to Regulate EMT and Tumor Survival.
Shao DD, Xue W, Krall EB, Bhutkar A, Piccioni F, Wang X, Schinzel AC, Sood S, Rosenbluh J, Kim JW, Zwang Y, Roberts TM, Root DE, Jacks T, Hahn WC
Cell. 2014 Jul 3;158(1):171-84. doi: 10.1016/j.cell.2014.06.004. Epub 2014 Jun 19.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
59140pLX304-FOS-V5wild-type FOS with C-terminal V5 tag expressed from pLX vector
Loading...
59141pLX304-YAP1 _SH3bmYAP1 mutants that harbored a deletion of SH3 binding motif, which disrupts interaction of YES1 with YAP1
Loading...
59143pLX304-YAP1 _TAYAP1 mutants that harbor a deletion of the transcriptional activation domain
Loading...
59144pLX304-YAP1 _60-89YAP1 mutants that harbored a deletion of amino acide at 60-89 position, which disrupts binding to TEAD transcription factors
Loading...
59145pLX304-YAP1(S94A)YAP1 serine 94 o alanine mutants which disrupts binding to TEAD transcription factors
Loading...
59147pLX304-YAP1 _PDZYAP1 mutants that harbored a deletion of the 5 amino acids
Loading...
59913TGMP.shKras.1422Tet on shKras for conditional Kras knockdown
Loading...
59915TRMPVneo.Yap.3093Tet on shRNA for conditional Yap1 knockdown
Loading...
116871Tet-pLKO-puro shKRASTet-inducible suppression of KRAS
Loading...

Antibodies from Article