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Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification.

Guilinger JP, Thompson DB, Liu DR
Nat Biotechnol. 2014 Apr 25. doi: 10.1038/nbt.2909. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
52970FokI-dCas9Expresses Fok1 nuclease domain fused to catalytically inactive Cas9 DNA-binding domain in mammalian cells

Antibodies from Article