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The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Savolainen MH, Richie CT, Harvey BK, Mannisto PT, Maguire-Zeiss KA, Myohanen TT
Neurobiol Dis. 2014 Aug;68:1-15. doi: 10.1016/j.nbd.2014.04.003. Epub 2014 Apr 16.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
59967pOTTC414 - pAAV EF1a hPREPAn AAV packaging vector that expresses hPREP under control of the EF1a promoter.
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59968pOTTC446 - pAAV EF1a hPREP(S554A)An AAV packaging vector that expresses catalytically-inactive hPREP under control of the EF1a promoter.
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60057pOTTC293 - pAAV EF1a V5-synuclein (WT)An AAV packaging vector that expresses wildtype alpha-synuclein under control of the EF1a promoter.
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60058pOTTC407 - pAAV EF1a eGFPAn AAV packaging vector that expresses enhanced green fluorescent protein under control of the EF1a promoter.
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Antibodies from Article