Conversion of Channelrhodopsin into a Light-Gated Chloride Channel.
Wietek J, Wiegert JS, Adeishvili N, Schneider F, Watanabe H, Tsunoda SP, Vogt A, Elstner M, Oertner TG, Hegemann P
Science. 2014 Mar 27. PubMed Article
Wietek J, Wiegert JS, Adeishvili N, Schneider F, Watanabe H, Tsunoda SP, Vogt A, Elstner M, Oertner TG, Hegemann P
Science. 2014 Mar 27. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 52494 | pAAV Syn ChR E90R-D156N-T159C 2A tDimer | Historical plasmid. For inhibition of neuronal activity, note that Addgene Plasmid #66709 is a light-gated chloride channel with improved anion selectivity (iChloC) |
| 52495 | pAAV Syn ChR E90R-T159C 2A tDimer | Historical plasmid. For inhibition of neuronal activity, note that Addgene Plasmid #66709 is a light-gated chloride channel with improved anion selectivity (iChloC) |
| 52878 | pAAV CaMKIIa ChR2 E90R D156N T159C 2A tDimer | Chloride-conducting Channelrhodopsin with slow kinetics, neuron-specific promoter, plus red fluorescent protein, excitatory neurons |
| 85461 | p-mCherry-N1-ChloC | Historical plasmid. For inhibition of neuronal activity, #66709 is a light-gated chloride channel with improved anion selectivity (iChloC) |
| 85462 | p-mCherry-N1-slowChloC | Historical plasmid. For inhibition of neuronal activity, #66709 is a light-gated chloride channel with improved anion selectivity (iChloC) |