The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart.

Kim HS, Chen Q, Kim SK, Nickoloff JA, Hromas R, Georgiadis MM, Lee SH
J Biol Chem. 2014 Apr 11;289(15):10930-8. doi: 10.1074/jbc.M113.533216. Epub 2014 Feb 25. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.