Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells.

Carpenter RL, Paw I, Dewhirst MW, Lo HW
Oncogene. 2015 Jan 29;34(5):546-57. doi: 10.1038/onc.2013.582. Epub 2014 Jan 27. PubMed Article

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