ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation.

Walker AK, Soo KY, Sundaramoorthy V, Parakh S, Ma Y, Farg MA, Wallace RH, Crouch PJ, Turner BJ, Horne MK, Atkin JD
PLoS One. 2013 Nov 29;8(11):e81170. doi: 10.1371/journal.pone.0081170. eCollection 2013. PubMed Article

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