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The membrane-proximal KXGFFKR motif of alpha-integrin mediates chemoresistance.
Liu CC, Leclair P, Yap SQ, Lim CJ
Mol Cell Biol. 2013 Nov;33(21):4334-45. doi: 10.1128/MCB.00580-13. Epub 2013 Sep 3.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
80016pcDNA3.1-alpha4 wtMammalian expression of human integrin alpha4
80017pcDNA3.1-alpha4 wt (Hygro)Mammalian expression of human integrin alpha4, Hygro selection
80018pcDNA3.1-a4-delta tailMammalian expression of human integrin alpha4 with no tail
80019pcDNA 3.1 (+) Tac-delta scrMammalian expression of Tac-delta scr
81177pcDNA 3.1 (+) TacδMammalian expression of human Tacδ (GFFKR cytoplasmic tail)

Antibodies from Article