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Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation.
Deschenes-Simard X, Gaumont-Leclerc MF, Bourdeau V, Lessard F, Moiseeva O, Forest V, Igelmann S, Mallette FA, Saba-El-Leil MK, Meloche S, Saad F, Mes-Masson AM, Ferbeyre G
Genes Dev. 2013 Apr 15;27(8):900-15. doi: 10.1101/gad.203984.112. Epub 2013 Apr 18.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
65228shERK1a-mlpx-puroencodes a shRNA against ERK1
65229shERK2a-mlpx-puroencodes a shRNA against ERK2
65230shERK2b-mlpx-puroencodes a shRNA against ERK2
65231shERK2b-mlpx-neoencodes a shRNA against ERK2
65232shCTL-mlpx-puroencodes a non-targeting control shRNA
65233shCTL-mlpx-neoencodes a non-targeting control shRNA

Antibodies from Article