Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism.

Buler M, Aatsinki SM, Izzi V, Hakkola J
PLoS One. 2012;7(11):e49863. doi: 10.1371/journal.pone.0049863. Epub 2012 Nov 16. PubMed Article

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