Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.
Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC
Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975. PubMed Article
Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC
Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 41806 | IL2 pAcGP67a | |
| 41807 | IL2 F42A pAcGP67a | |
| 41808 | IL2 pMalLP | |
| 41810 | H9 F42A pAcGP67a | |
| 41811 | H9 pMalLP | |
| 41812 | D10 pAcGP67a |