Activation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an auto-inhibitory linker.

Ben-Aissa K, Patino-Lopez G, Belkina NV, Maniti O, Rosales T, Hao JJ, Kruhlak MJ, Knutson JR, Picart C, Shaw S
J Biol Chem. 2012 Mar 23. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.