Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.

Gonzalez P, Mader I, Tchoghandjian A, Enzenmuller S, Cristofanon S, Basit F, Debatin KM, Fulda S
Cell Death Differ. 2012 Aug;19(8):1337-46. doi: 10.1038/cdd.2012.10. Epub 2012 Feb 17. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.