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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.
Anastasiou D, Poulogiannis G, Asara JM, Boxer MB, Jiang JK, Shen M, Bellinger G, Sasaki AT, Locasale JW, Auld DS, Thomas CJ, Vander Heiden MG, Cantley LC
Science. 2011 Dec 2;334(6060):1278-83. doi: 10.1126/science.1211485. Epub 2011 Nov 3.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
42511pLHCX-Flag-mPKM1
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42513pLHCX-Flag-mPKM2(C358S)
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42514pLHCX-Flag-mPKM2(K433E)
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42515pET28a-His-hPKM2
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42516pLKO-shPKM2_4
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Antibodies from Article