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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y
Science. 2011 Sep 2;333(6047):1300-3. doi: 10.1126/science.1210597. Epub 2011 Jul 21. PubMed Article

Plasmids from Article

ID Plasmid Purpose
70129pcDNA3-Flag-Tet1 CDExpress flag-tagged mouse Tet1 catalytic domain.
72218pcDNA3-Flag-Tet1 CD MutExpress flag-tagged mouse Tet1 catalytic domain - catalytic dead mutant.
72219pcDNA3-Flag-Tet2 CDExpress flag-tagged mouse Tet2 catalytic domain.
72220pcDNA3-Flag-Tet2 CD MutExpress flag-tagged mouse Tet2 catalytic domain - catalytic dead mutant.
72222pcDNA3-Flag-Tet3 CD MutExpress flag-tagged mouse Tet3 catalytic domain - catalytic dead mutant.

Antibodies from Article