Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition.

Schvartzman JM, Duijf PH, Sotillo R, Coker C, Benezra R
Cancer Cell. 2011 Jun 14;19(6):701-14. doi: 10.1016/j.ccr.2011.04.017. PubMed Article

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