Evaluation of loss of function as an explanation for SPG4-based hereditary spastic paraplegia.
Solowska JM, Garbern JY, Baas PW
Hum Mol Genet. 2010 Jul 15;19(14):2767-79. doi: 10.1093/hmg/ddq177. Epub 2010 Apr 29.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 87715 | pCMV-Tag 3A/myc-M1E112K | Expresses myc-M1E112K spastin isoform in mammalian cells |
| 87716 | pCMV-Tag 3A/myc-M1L195V | Expresses myc-M1L195V spastin isoform in mammalian cells |
| 87717 | pCMV-Tag 3A/myc-M1S44L | Expresses myc-M1S44L spastin isoform in mammalian cells |
| 87718 | pCMV-Tag 3A/myc-M1S46X | Expresses myc-M1S46X spastin isoform in mammalian cells |
| 87719 | pCMV-Tag 3A/WT myc-M1 | Expresses WT myc-M1 spastin isoform in mammalian cells |
| 87720 | pCMV-Tag 3B/myc-M87E112K | Expresses myc-M87E112K spastin isoform in mammalian cells |
| 87721 | pCMV-Tag 3B/myc-M87L195V | Expresses myc-M87L195V spastin isoform in mammalian cells |
| 87722 | pCMV-Tag 3B/WT myc-M87 | Expresses WT myc-M87 spastin isoform in mammalian cells |
| 87723 | pCMV-Tag/E112K with 5'UTR | Expresses E112K spastin M1 and M87 in mammalian cells |
| 87724 | pCMV-Tag/E112K without 5'UTR | Expresses E112K spastin M1 and M87 in mammalian cells |
| 87725 | pCMV-Tag/L195V with 5'UTR | Expresses L195V spastin M1 and M87 in mammalian cells |
| 87726 | pCMV-Tag/L195V without 5'UTR | Expresses L195V spastin M1 and M87 in mammalian cells |
| 87727 | pCMV-Tag/S44L with 5'UTR | Expresses S44L spastin M1 and M87 in mammalian cells |
| 87728 | pCMV-Tag/S44L without 5'UTR | Expresses S44L spastin M1 and M87 in mammalian cells |
| 87729 | pCMV-Tag/S46X with 5'UTR | Expresses S46X spastin M1 and M87 in mammalian cells |
| 87730 | pCMV-Tag/S46X without 5'UTR | Expresses S46X spastin M1 and M87 in mammalian cells |
| 87731 | pCMV-Tag/WT SPAST with 5'UTR | Expresses WT spastin M1 and M87 in mammalian cells |
| 87732 | pCMV-Tag/WT SPAST without 5'UTR | Expresses WT spastin M1 and M87 in mammalian cells |