Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.
Neagu MR, Ziegler P, Pertel T, Strambio-De-Castillia C, Grutter C, Martinetti G, Mazzucchelli L, Grutter M, Manz MG, Luban J
J Clin Invest. 2009 Oct;119(10):3035-47. doi: 10.1172/JCI39354. Epub 2009 Sep 8. PubMed Article
Neagu MR, Ziegler P, Pertel T, Strambio-De-Castillia C, Grutter C, Martinetti G, Mazzucchelli L, Grutter M, Manz MG, Luban J
J Clin Invest. 2009 Oct;119(10):3035-47. doi: 10.1172/JCI39354. Epub 2009 Sep 8. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 80279 | pFUPI | A bicistronic lentiviral vector used to stably express cDNAs. |
| 80280 | pFUPI AoT5Cyp | Expresses Aotus TRIM5 CypA fusion |
| 80281 | pFUPI hT5Cyp-H126Q | Expresses human TRIM5 CypA fusion with H126Q mutation in CypA |
| 80282 | pFUPI hT5-S322-Cyp | Expresses human TRIM5 CypA fusion |