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Interfering with glycolysis causes Sir2-dependent hyper-recombination of Saccharomyces cerevisiae plasmids.
Ralser M, Zeidler U, Lehrach H
PLoS One. 2009;4(4):e5376. doi: 10.1371/journal.pone.0005376. Epub 2009 Apr 24. PubMed Article

Plasmids from Article

ID Plasmid Purpose
51742p413TEF-Sir2overexpression of Sir2 in S. cerevisiae, HIS3 marker
51743p413TEF-Sir2-H364Yoverexpression of Sir2 in S. cerevisiae (H364Y mutant), HIS3 marker
51744p413TEF-Sir2-P394Loverexpression of Sir2 in S. cerevisiae (P394L mutant), HIS3 marker
51745p413TEF-HST2overexpression of HST2 in S. cerevisiae, HIS3 marker
51746p413TEF-SirT1overexpression of human SirT1 in S. cerevisiae, HIS3 marker

Antibodies from Article