A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75.

Hare S, Shun MC, Gupta SS, Valkov E, Engelman A, Cherepanov P
PLoS Pathog. 2009 Jan;5(1):e1000259. doi: 10.1371/journal.ppat.1000259. Epub 2009 Jan 9. PubMed Article

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