COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression.

Kato S, Ding J, Pisck E, Jhala US, Du K
J Biol Chem. 2008 Dec 19;283(51):35464-73. doi: 10.1074/jbc.M801011200. Epub 2008 Sep 24. PubMed Article

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