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GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay.
Eulalio A, Huntzinger E, Izaurralde E
Nat Struct Mol Biol. 2008 Apr . 15(4):346-53. PubMed Article

Plasmids from Article

ID Plasmid Purpose
22768pAc5.1B-EGFP-DmAGO1
145896pAc5.1B-lambdaN-HA-DmAGO1-F2V2_AInsect Expression of DmAGO1-F2V2
145897pAc5.1B-lambdaN-HA-DmAGO1-F594V_AInsect Expression of DmAGO1-F594V
145898pAc5.1B-lambdaN-HA-DmAGO1-F629V_AInsect Expression of DmAGO1-F629V
145899pAc5.1B-lambdaN-HA-DmAGO1-siRNAres_AInsect Expression of DmAGO1-siRNAres
145900pAc5.1C-Fluc-CG11206_AInsect Expression of CG11206-3UTR
146224pAc5.1B-lambdaN-HA-HsAGO2_EInsect Expression of HsAGO2
146225pAc5.1B-lambdaN-HA-HsAGO2-F470V_EInsect Expression of HsAGO2-F470V
146226pAc5.1B-lambdaN-HA-HsAGO2-F505V_EInsect Expression of HsAGO2-F505V
146227pAc5.1C-Fluc-CG11206-HSL_EInsect Expression of CG11206-3UTR
146228pAc5.1C-Fluc-nerfin-HSL_EInsect Expression of Nerfin-3UTR
146285pAc5.1B-EGFP-DmGW182_1-592_FInsect Expression of DmGW182_1-592
146286pAc5.1B-lambdaN-HA-HsAGO2-F2V2_FInsect Expression of HsAGO2-F2V2
146287pCIneo-lambdaN-HA-HsAGO2-F2V2_FMammalian Expression of HsAGO2-F2V2
146288pCIneo-lambdaN-HA-HsAGO2-F470V_FMammalian Expression of HsAGO2-F470V
146289pCIneo-lambdaN-HA-HsAGO2-F505V_FMammalian Expression of HsAGO2-F505V
146399pAc5.1B-lambdaN-HA-DmGW182_1-592_GInsect Expression of DmGW182_1-592

Antibodies from Article