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Protein phosphatase 2A and separase form a complex regulated by separase autocleavage.
Holland AJ, Bottger F, Stemmann O, Taylor SS
J Biol Chem. 2007 Aug 24;282(34):24623-32. Epub 2007 Jun 29. PubMed Article

Plasmids from Article

ID Plasmid Purpose
59824pcDNA5 FRT TO myc Separase delta 55Allows the integration of myc Separase delta 55 in the genome and Tet-inducible expression.
59825pcDNA5 FRT TO myc Separase delta 55/S1126AAllows the integration of myc Separase delta 55/S1126A in the genome and Tet-inducible expression.
59826pcDNA5 FRT TO myc Separase Non-CleavableAllows the integration of myc Separase Non-Cleavable in the genome and Tet-inducible expression.
59827pcDNA5 FRT TO myc Separase delta 55/Non-CleavableAllows the integration of myc Separase delta 55/Non-Cleavable in the genome and Tet-inducible expression.
59830pcDNA5 FRT TO myc Separase delta 1278-1291Allows the integration of myc Separase delta 1278-1291 in the genome and Tet-inducible expression.

Antibodies from Article