Robin Shaw Lab Materials

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Title	Authors	Publication
A 14-3-3 Mode-1 Binding Motif Initiates Gap Junction Internalization during Acute Cardiac Ischemia.	Smyth JW, Zhang SS, Sanchez JM, Lamouille S, Vogan JM, Hesketh GG, Hong T, Tomaselli GF, Shaw RM	Traffic. 2014 Mar 10. doi: 10.1111/tra.12169.
Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane.	Smyth JW, Vogan JM, Buch PJ, Zhang SS, Fong TS, Hong TT, Shaw RM	Circ Res. 2012 Mar 30;110(7):978-89. Epub 2012 Feb 9.
Autoregulation of Connexin43 Gap Junction Formation by Internally Translated Isoforms.	Smyth JW, Shaw RM	Cell Rep. 2013 Nov 5. pii: S2211-1247(13)00578-0. doi: 10.1016/j.celrep.2013.10.009.
BIN1 localizes the L-type calcium channel to cardiac T-tubules.	Hong TT, Smyth JW, Gao D, Chu KY, Vogan JM, Fong TS, Jensen BC, Colecraft HM, Shaw RM	PLoS Biol. 2010 Feb . 8(2):e1000312.
Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.	Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marban E, Jan LY, Shaw RM	Nat Med. 2014 Jun;20(6):624-32. doi: 10.1038/nm.3543. Epub 2014 May 18.
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium.	Smyth JW, Hong TT, Gao D, Vogan JM, Jensen BC, Fong TS, Simpson PC, Stainier DY, Chi NC, Shaw RM	J Clin Invest. 2010 Jan 4. 120(1):266-79.

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.47.922720.31796	31796	pDest-eGFP-N1		Mammalian Expression	BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol. 2010 Feb . 8(2):e1000312.
100.3.999055.31907	31907	pDest-mCherry-N1		Mammalian Expression	BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol. 2010 Feb . 8(2):e1000312.
100.2.277142.40908	40908	pDEST/LIfeAct-mCherry-N1	LifeAct	Mammalian Expression	Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res. 2012 Mar 30;110(7):978-89. Epub 2012 Feb 9.
50.25.714849.49851	49851	pcDNA3.2-Cx43-HA	Connexin 43 (GJA1 Human)	Mammalian Expression	Autoregulation of Connexin43 Gap Junction Formation by Internally Translated Isoforms. Cell Rep. 2013 Nov 5. pii: S2211-1247(13)00578-0. doi: 10.1016/j.celrep.2013.10.009.
50.24.965439.40907	40907	pDEST/hCx43-EGFP-N1	Connexin 43 (GJA1 Human)	Mammalian Expression	Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res. 2012 Mar 30;110(7):978-89. Epub 2012 Feb 9.
50.3.542366.69610	69610	pcDNA3.2/DEST/hTfR-HA	human transferrin receptor (TFRC Human)	Mammalian Expression	Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res. 2012 Mar 30;110(7):978-89. Epub 2012 Feb 9.
20.7.211257.49861	49861	pDEST-mCherry-GJA1-20k-N1	GJA1-20k (GJA1 Human)	Mammalian Expression	Autoregulation of Connexin43 Gap Junction Formation by Internally Translated Isoforms. Cell Rep. 2013 Nov 5. pii: S2211-1247(13)00578-0. doi: 10.1016/j.celrep.2013.10.009.
20.1.458329.27305	27305	pDEST/N1-hBIN1-GFP	bridging integrator 1 (BIN1), transcript variant 8 (BIN1 Human)	Mammalian Expression	BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol. 2010 Feb . 8(2):e1000312.
20.0.366911.27383	27383	plenti6.3/hCx43-stop	Gja1 (GJA1 Human)	Mammalian Expression, Lentiviral	Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest. 2010 Jan 4. 120(1):266-79.
20.0.171932.31807	31807	pTRE-TIGHT-Cx43-eYFP	Cx43 (GJA1 Human)	Mammalian Expression	Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest. 2010 Jan 4. 120(1):266-79.