A comprehensive library of human transcription factors for cell fate engineering. | Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL, Appleton E, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J, Hill DE, Vidal M, Melero-Martin JM, Busskamp V, Church GM | Nat Biotechnol. 2021 Apr;39(4):510-519. doi: 10.1038/s41587-020-0742-6. Epub 2020 Nov 30. |
A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans. | Shapiro RS, Chavez A, Porter CBM, Hamblin M, Kaas CS, DiCarlo JE, Zeng G, Xu X, Revtovich AV, Kirienko NV, Wang Y, Church GM, Collins JJ | Nat Microbiol. 2018 Jan;3(1):73-82. doi: 10.1038/s41564-017-0043-0. Epub 2017 Oct 23. |
A multifunctional AAV-CRISPR-Cas9 and its host response. | Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM | Nat Methods. 2016 Sep 5. doi: 10.1038/nmeth.3993. |
A swapped genetic code prevents viral infections and gene transfer. | Nyerges A, Vinke S, Flynn R, Owen SV, Rand EA, Budnik B, Keen E, Narasimhan K, Marchand JA, Baas-Thomas M, Liu M, Chen K, Chiappino-Pepe A, Hu F, Baym M, Church GM | Nature. 2023 Mar;615(7953):720-727. doi: 10.1038/s41586-023-05824-z. Epub 2023 Mar 15. |
Adaptive evolution of genomically recoded Escherichia coli. | Wannier TM, Kunjapur AM, Rice DP, McDonald MJ, Desai MM, Church GM | Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3090-3095. doi: 10.1073/pnas.1715530115. Epub 2018 Feb 13. |
An enhanced CRISPR repressor for targeted mammalian gene regulation. | Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM | Nat Methods. 2018 Jul 16. pii: 10.1038/s41592-018-0048-5. doi: 10.1038/s41592-018-0048-5. |
An integrated pipeline for mammalian genetic screening. | Kramme C, Plesa AM, Wang HH, Wolf B, Smela MP, Guo X, Kohman RE, Chatterjee P, Church GM | Cell Rep Methods. 2021 Sep 27;1(6):100082. doi: 10.1016/j.crmeth.2021.100082. eCollection 2021 Oct 25. |
Barcoding cells using cell-surface programmable DNA-binding domains. | Mali P, Aach J, Lee JH, Levner D, Nip L, Church GM | Nat Methods. 2013 Mar 17. doi: 10.1038/nmeth.2407. |
Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators. | Juarez JF, Lecube-Azpeitia B, Brown SL, Johnston CD, Church GM | Nat Commun. 2018 Aug 6;9(1):3101. doi: 10.1038/s41467-018-05525-6. |
Broad-host-range plasmids for improved recombineering in Gammaproteobacteria | (unpublished) | |