Georgia Konstantinidou Lab Materials

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Title	Authors	Publication
ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer.	Pozzato C, Outeiro-Pinho G, Galie M, Ramadori G, Konstantinidou G	EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
	216540	pWZL-hygro-FAKWT	PTK2 (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216541	pWZL-hygro-FAKS732A	PTK2 (S732A) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216542	pWZL-hygro-FAKS910A	PTK2 (S910A) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216543	pWZL-hygro-FAKR177/178A	PTK2 (R177/178A) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216544	pWZL-hygro-FAKP712/713A	PTK2 (P712/713A) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216545	pWZL-hygro-FAKS722A	PTK2 (S722A) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216546	pWZL-hygro-FAKY861F	PTK2 (Y861F) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216547	pWZL-hygro-FAKY925F	PTK2 (Y925F) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	216677	pWZL-hygro-FAKY397F	PTK2 (Y397F) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
	221642	pWZL-hygro-FAKS732A/S910A	PTK2 (S732A/S910A) (PTK2 Human)	Mammalian Expression, Retroviral	ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.