A naturally monomeric infrared fluorescent protein for protein labeling in vivo. | Yu D, Baird MA, Allen JR, Howe ES, Klassen MP, Reade A, Makhijani K, Song Y, Liu S, Murthy Z, Zhang SQ, Weiner OD, Kornberg TB, Jan YN, Davidson MW, Shu X | Nat Methods. 2015 Aug;12(8):763-765. doi: 10.1038/nmeth.3447. Epub 2015 Jun 22. |
A rapid fluorogenic GPCR-beta-arrestin interaction assay. | Zhang Q, Zheng YW, Coughlin SR, Shu X | Protein Sci. 2018 Apr;27(4):874-879. doi: 10.1002/pro.3385. Epub 2018 Feb 23. |
An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. | Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X | Nat Commun. 2014 May 15;5:3626. doi: 10.1038/ncomms4626. |
ATM-SPARK: A GFP phase separation-based activity reporter of ATM. | Li X, Chung CI, Yang J, Chaudhuri S, Munster PN, Shu X | Sci Adv. 2023 Mar;9(9):eade3760. doi: 10.1126/sciadv.ade3760. Epub 2023 Mar 1. |
Chemogenetic Minitool for Dissecting the Roles of Protein Phase Separation. | Chung CI, Yang J, Shu X | ACS Cent Sci. 2023 Jul 7;9(7):1466-1479. doi: 10.1021/acscentsci.3c00251. eCollection 2023 Jul 26. |
Designing a green fluorogenic protease reporter by flipping a beta strand of GFP for imaging apoptosis in animals. | Zhang Q, Schepis A, Huang H, Yang J, Ma W, Torra J, Zhang SQ, Yang L, Wu H, Nonell S, Dong Z, Kornberg TB, Coughlin SR, Shu X | J Am Chem Soc. 2019 Mar 1. doi: 10.1021/jacs.8b13042. |
Ethacridine inhibits SARS-CoV-2 by inactivating viral particles. | Li X, Lidsky P, Xiao Y, Wu CT, Garcia-Knight M, Yang J, Nakayama T, Nayak JV, Jackson PK, Andino R, Shu X | PLoS Pathog. 2021 Sep 3;17(9):e1009898. doi: 10.1371/journal.ppat.1009898. |
FlipGFP-based activity reporter of SARS-CoV-2 main protease Mpro | (unpublished) | |
Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2. | Yang J, Xiao Y, Lidsky PV, Wu CT, Bonser LR, Peng S, Garcia-Knight MA, Tassetto M, Chung CI, Li X, Nakayama T, Lee IT, Nayak JV, Ghias K, Hargett KL, Shoichet BK, Erle DJ, Jackson PK, Andino R, Shu X | Nat Microbiol. 2023 Jan;8(1):121-134. doi: 10.1038/s41564-022-01288-5. Epub 2023 Jan 5. |
Phase separation of YAP-MAML2 differentially regulates the transcriptome. | Chung CI, Yang J, Yang X, Liu H, Ma Z, Szulzewsky F, Holland EC, Shen Y, Shu X | Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2310430121. doi: 10.1073/pnas.2310430121. Epub 2024 Feb 5. |