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Kosuke Yusa Lab Materials
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Log in to manage alerts| Title | Authors | Publication |
|---|---|---|
| A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia. | Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJ, Iorio F, Pina C, Vassiliou GS, Yusa K | Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079. |
| Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia. | Aoki K, Hyuga M, Tarumoto Y, Nishibuchi G, Ueda A, Ochi Y, Sugino S, Mikami T, Kobushi H, Kato I, Akahane K, Inukai T, Takaori-Kondo A, Takita J, Ogawa S, Yusa K | Blood. 2023 Nov 3:blood.2023020857. doi: 10.1182/blood.2023020857. |
| Cas9 expression in iPSCs using AAVS1-CAGCas9neo | (unpublished) | |
| CRISPR-KO screen identifies Dmap1 as a regulator of chemically-induced reprogramming and differentiation of cardiac progenitors. | Yu JSL, Palano G, Lim C, Moggio A, Drowley L, Plowright AT, Bohlooly-Y M, Rosen BS, Hansson EM, Wang QD, Yusa K | Stem Cells. 2019 Apr 1. doi: 10.1002/stem.3012. |
| Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution. | Li M, Yu JSL, Tilgner K, Ong SH, Koike-Yusa H, Yusa K | Cell Rep. 2018 Jul 10;24(2):489-502. doi: 10.1016/j.celrep.2018.06.027. |
| Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library. | Koike-Yusa H, Li Y, Tan EP, Velasco-Herrera Mdel C, Yusa K | Nat Biotechnol. 2014 Mar;32(3):267-73. doi: 10.1038/nbt.2800. Epub 2013 Dec 23. |
| KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements. | Au YZ, Gu M, De Braekeleer E, Gozdecka M, Aspris D, Tarumoto Y, Cooper J, Yu J, Ong SH, Chen X, Tzelepis K, Huntly BJP, Vassiliou G, Yusa K | Leukemia. 2021 Apr;35(4):1012-1022. doi: 10.1038/s41375-020-1001-z. Epub 2020 Aug 6. |
| Pooled extracellular receptor-ligand interaction screening using CRISPR activation. | Chong ZS, Ohnishi S, Yusa K, Wright GJ | Genome Biol. 2018 Nov 26;19(1):205. doi: 10.1186/s13059-018-1581-3. |
| RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations. | Ishikawa M, Sugino S, Masuda Y, Tarumoto Y, Seto Y, Taniyama N, Wagai F, Yamauchi Y, Kojima Y, Kiryu H, Yusa K, Eiraku M, Mochizuki A | Commun Biol. 2023 Dec 28;6(1):1290. doi: 10.1038/s42003-023-05594-4. |
| Yusa CRISPR-Cas9 and mammalian expression plasmids | (unpublished) |
| ID | Pooled Library | Vector Type | Publication | |
|---|---|---|---|---|
100.11.121263.67988 | 67988 | Mouse genome-wide lentiviral CRISPR gRNA library version 2 | Lentiviral, CRISPR | A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia. Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079. |
100.4.761434.67989 | 67989 | Human genome-wide lentiviral CRISPR gRNA library version 1 | Lentiviral, CRISPR | A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia. Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079. |