Adeno-associated virus effectively mediates conditional gene modification in the brain. | Kaspar BK, Vissel B, Bengoechea T, Crone S, Randolph-Moore L, Muller R, Brandon EP, Schaffer D, Verma IM, Lee KF, Heinemann SF, Gage FH | Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2320-5. Epub 2002 Feb 12. |
Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons. | Herdy J, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola A, Lee H, Mertens J, Gage FH | Elife. 2019 May 17;8. pii: 41356. doi: 10.7554/eLife.41356. |
Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. | Mertens J, Paquola AC, Ku M, Hatch E, Bohnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Goncalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH | Cell Stem Cell. 2015 Oct 6. pii: S1934-5909(15)00408-7. doi: 10.1016/j.stem.2015.09.001. |
Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. | Zhao C, Teng EM, Summers RG, Ming GL, Gage FH | J Neurosci. 2006 Jan 4. 26(1):3-11. |
Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. | Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH | Cell Stem Cell. 2008 Dec 4;3(6):649-57. |
Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. | Schafer ST, Paquola ACM, Stern S, Gosselin D, Ku M, Pena M, Kuret TJM, Liyanage M, Mansour AA, Jaeger BN, Marchetto MC, Glass CK, Mertens J, Gage FH | Nat Neurosci. 2019 Feb;22(2):243-255. doi: 10.1038/s41593-018-0295-x. Epub 2019 Jan 7. |
Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo. | Tashiro A, Zhao C, Gage FH | Nat Protoc. 2006;1(6):3049-55. |