David Rubinsztein Lab Materials

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Title	Authors	Publication
A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.	Puri C, Manni MM, Vicinanza M, Hilcenko C, Zhu Y, Runwal G, Stamatakou E, Menzies FM, Mamchaoui K, Bitoun M, Rubinsztein DC	Dev Cell. 2020 Apr 20;53(2):154-168.e6. doi: 10.1016/j.devcel.2020.03.018.
A molecular investigation of true dominance in Huntington's disease.	Narain Y, Wyttenbach A, Rankin J, Furlong RA, Rubinsztein DC	J Med Genet. 1999 Oct;36(10):739-46.
Alpha-synuclein overexpression promotes aggregation of mutant huntingtin.	Furlong RA, Narain Y, Rankin J, Wyttenbach A, Rubinsztein DC	Biochem J. 2000 Mar 15;346 Pt 3:577-81.
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A.	Son SM, Park SJ, Lee H, Siddiqi F, Lee JE, Menzies FM, Rubinsztein DC	Cell Metab. 2019 Jan 8;29(1):192-201.e7. doi: 10.1016/j.cmet.2018.08.013. Epub 2018 Sep 6.
p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol.	Wrobel L, Hoffmann JL, Li X, Rubinsztein DC	Sci Adv. 2024 May 3;10(18):eadl6082. doi: 10.1126/sciadv.adl6082. Epub 2024 May 3.
PSMC5 insufficiency and P320R mutation impair proteasome function.	Yu ZQ, Carmichael J, Collins GA, D'Agostino MD, Lessard M, Firth HV, Harijan P, Fry AE, Dean J, Zhang J, Kini U, Goldberg AL, Rubinsztein DC	Hum Mol Genet. 2024 May 22:ddae085. doi: 10.1093/hmg/ddae085.
The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes.	Jahreiss L, Menzies FM, Rubinsztein DC	Traffic. 2008 Apr;9(4):574-87. Epub 2008 Jan 7.

Showing 1 to 10 of 21 entries

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.478.473798.40823	40823	EGFP-alphasynuclein-A53T	SNCA (SNCA Human)	Mammalian Expression	Alpha-synuclein overexpression promotes aggregation of mutant huntingtin. Biochem J. 2000 Mar 15;346 Pt 3:577-81.
100.145.453002.40827	40827	mCherry-hLC3B-pcDNA3.1	LC3B (MAP1LC3B Human)	Mammalian Expression	The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes. Traffic. 2008 Apr;9(4):574-87. Epub 2008 Jan 7.
100.70.171810.40822	40822	EGFP-alphasynuclein-WT	SNCA (SNCA Human)	Mammalian Expression	Alpha-synuclein overexpression promotes aggregation of mutant huntingtin. Biochem J. 2000 Mar 15;346 Pt 3:577-81.
100.29.013039.40261	40261	pEGFP-Q23	HTT partial exon 1 Q23 (HTT Human)	Mammalian Expression	A molecular investigation of true dominance in Huntington's disease. J Med Genet. 1999 Oct;36(10):739-46.
100.28.349420.40262	40262	pEGFP-Q74	HTT partial exon 1 Q74 (HTT Human)	Mammalian Expression	A molecular investigation of true dominance in Huntington's disease. J Med Genet. 1999 Oct;36(10):739-46.
100.21.263447.40825	40825	pHM6-alphasynuclein-A53T	SNCA (SNCA Human)	Mammalian Expression	Alpha-synuclein overexpression promotes aggregation of mutant huntingtin. Biochem J. 2000 Mar 15;346 Pt 3:577-81.
100.13.764214.40824	40824	pHM6-alphasynuclein-WT	SNCA (SNCA Human)	Mammalian Expression	Alpha-synuclein overexpression promotes aggregation of mutant huntingtin. Biochem J. 2000 Mar 15;346 Pt 3:577-81.
50.201.234040.40264	40264	pHM6-Q74	HTT partial exon 1 Q74 (HTT Human)	Mammalian Expression	A molecular investigation of true dominance in Huntington's disease. J Med Genet. 1999 Oct;36(10):739-46.
50.194.985987.40263	40263	pHM6-Q23	HTT partial exon 1 Q23 (HTT Human)	Mammalian Expression	A molecular investigation of true dominance in Huntington's disease. J Med Genet. 1999 Oct;36(10):739-46.
	155262	pcDNA3-HA-DNM2-R465W	dynamin 2 (Dnm2 Rat)	Mammalian Expression	A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy. Dev Cell. 2020 Apr 20;53(2):154-168.e6. doi: 10.1016/j.devcel.2020.03.018.