Titia de Lange Lab Materials

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Title	Authors	Publication
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.	Dimitrova N, Chen YC, Spector DL, de Lange T	Nature. 2008 Oct 19. ():.
A human telomeric protein.	Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J, Tempst P, de Lange T	Science. 1995 Dec 8. 270(5242):1663-7.
Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains.	Broccoli D, Chong L, Oelmann S, Fernald AA, Marziliano N, van Steensel B, Kipling D, Le Beau MM, de Lange T	Hum Mol Genet. 1997 Jan . 6(1):69-76.
de Lange Lab Vectors	(unpublished)
Different telomere damage signaling pathways in human and mouse cells.	Smogorzewska A, de Lange T	EMBO J. 2002 Aug 15. 21(16):4338-48.
Human telomeres are attached to the nuclear matrix.	de Lange T	EMBO J. 1992 Feb . 11(2):717-24.
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.	Broccoli D, Smogorzewska A, Chong L, de Lange T	Nat Genet. 1997 Oct . 17(2):231-5.
Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.	Sfeir A, Kabir S, van Overbeek M, Celli GB, de Lange T	Science. 2010 Mar 26;327(5973):1657-61. doi: 10.1126/science.1185100.
POT1 as a terminal transducer of TRF1 telomere length control.	Loayza D, De Lange T	Nature. 2003 Jun 26. 423(6943):1013-8.
Rap1 affects the length and heterogeneity of human telomeres.	Li B, de Lange T	Mol Biol Cell. 2003 Dec . 14(12):5060-8.

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.33.178250.12403	12403	pSXneo 270(T2AG3)	270(T2AG3)	Mammalian Expression	Stringent sequence requirements for the formation of human telomeres. Proc Natl Acad Sci U S A. 1994 Sep 13. 91(19):8861-5.
100.29.022896.19836	19836	N-Myc-53BP1 WT pLPC-Puro	p53 Binding Protein 1 (TP53BP1 Human)	Retroviral	53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature. 2008 Oct 19. ():.
100.4.187545.19835	19835	mCherry-BP1-2 pLPC-Puro	Fragment of p53-Binding Protein 1 (TP53BP1 Human)	Retroviral	53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature. 2008 Oct 19. ():.
100.1.068745.12387	12387	pLPC myc hPOT1	Protection of Telomeres 1 (POT1 Human)	Retroviral	POT1 as a terminal transducer of TRF1 telomere length control. Nature. 2003 Jun 26. 423(6943):1013-8.
50.7.380806.16058	16058	pLPC-NFLAG TRF1	hTRF1 (TERF1 Human)	Retroviral	Different telomere damage signaling pathways in human and mouse cells. EMBO J. 2002 Aug 15. 21(16):4338-48.
50.6.936315.12542	12542	pLPC hRap1-FL	Repressor Activator Protein 1 (TERF2IP Human)	Retroviral	Rap1 affects the length and heterogeneity of human telomeres. Mol Biol Cell. 2003 Dec . 14(12):5060-8.
50.1.919072.16066	16066	pLPC-NMYC TRF2	hTRF2 (TERF2 Human)	Retroviral	Different telomere damage signaling pathways in human and mouse cells. EMBO J. 2002 Aug 15. 21(16):4338-48.
50.1.026691.16069	16069	pLPC-NMYC TRF2 deltaB deltaM	hTRF2 (TERF2 Human)	Retroviral	Different telomere damage signaling pathways in human and mouse cells. EMBO J. 2002 Aug 15. 21(16):4338-48.
50.0.890862.12540	12540	pLPC-N MYC	N MYC	Mammalian Expression, Retroviral	de Lange Lab Vectors (unpublished)
50.0.884859.19834	19834	eGFP-TRF1 pWzl-Hygro	Telomere-Repeat binding Factor 1 (Terf1 Mouse)	Retroviral	53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature. 2008 Oct 19. ():.