Jin-Soo Kim Lab Materials

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Title	Authors	Publication
A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system.	Kim H, Kim ST, Ryu J, Choi MK, Kweon J, Kang BC, Ahn HM, Bae S, Kim JS, Kim SG	J Integr Plant Biol. 2016 Mar 4. doi: 10.1111/jipb.12474.
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy.	Ryu SM, Koo T, Kim K, Lim K, Baek G, Kim ST, Kim HS, Kim DE, Lee H, Chung E, Kim JS	Nat Biotechnol. 2018 Jul;36(6):536-539. doi: 10.1038/nbt.4148. Epub 2018 Apr 27.
Base editing in human cells with monomeric DddA-TALE fusion deaminases.	Mok YG, Lee JM, Chung E, Lee J, Lim K, Cho SI, Kim JS	Nat Commun. 2022 Jul 12;13(1):4038. doi: 10.1038/s41467-022-31745-y.
Chloroplast and mitochondrial DNA editing in plants.	Kang BC, Bae SJ, Lee S, Lee JS, Kim A, Lee H, Baek G, Seo H, Kim J, Kim JS	Nat Plants. 2021 Jul;7(7):899-905. doi: 10.1038/s41477-021-00943-9. Epub 2021 Jul 1.
Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA.	Cho SI, Lim K, Hong S, Lee J, Kim A, Lim CJ, Ryou S, Lee JM, Mok YG, Chung E, Kim S, Han S, Cho SM, Kim J, Kim EK, Nam KH, Oh Y, Choi M, An TH, Oh KJ, Lee S, Lee H, Kim JS	Cell. 2024 Jan 4;187(1):95-109.e26. doi: 10.1016/j.cell.2023.11.035.
Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells.	Kim D, Kim J, Hur JK, Been KW, Yoon SH, Kim JS	Nat Biotechnol. 2016 Jun 6. doi: 10.1038/nbt.3609.
Genome-wide specificity of dCpf1 cytidine base editors.	Kim D, Lim K, Kim DE, Kim JS	Nat Commun. 2020 Aug 13;11(1):4072. doi: 10.1038/s41467-020-17889-9.
Highly efficient RNA-guided base editing in mouse embryos.	Kim K, Ryu SM, Kim ST, Baek G, Kim D, Lim K, Chung E, Kim S, Kim JS	Nat Biotechnol. 2017 Feb 27. doi: 10.1038/nbt.3816.
In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni.	Kim E, Koo T, Park SW, Kim D, Kim K, Cho HY, Song DW, Lee KJ, Jung MH, Kim S, Kim JH, Kim JH, Kim JS	Nat Commun. 2017 Feb 21;8:14500. doi: 10.1038/ncomms14500.
Mitochondrial DNA editing in mice with DddA-TALE fusion deaminases.	Lee H, Lee S, Baek G, Kim A, Kang BC, Seo H, Kim JS	Nat Commun. 2021 Feb 19;12(1):1190. doi: 10.1038/s41467-021-21464-1.

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.1.941534.79008	79008	pMAL-his-LbCpf1-EC	LbCpf1	Bacterial Expression	Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nat Biotechnol. 2016 Jun 6. doi: 10.1038/nbt.3609.
50.3.042971.112872	112872	pJY-RpABE	RPS5A promoter, ABE7.10, U6-sgRNA cassette	Plant Expression, CRISPR	Precision genome engineering through adenine base editing in plants. Nat Plants. 2018 Jun 4. pii: 10.1038/s41477-018-0178-x. doi: 10.1038/s41477-018-0178-x.
50.1.260552.79007	79007	pDEST-hisMBP-AsCpf1-EC	AsCpf1	Bacterial Expression	Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins. Nat Biotechnol. 2016 Jun 6. doi: 10.1038/nbt.3596.
20.55.078933.183892	183892	TALED_Left-ND1-1397C-AD	TALED for ND1 mutation	Mammalian Expression	Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases. Cell. 2022 May 12;185(10):1764-1776.e12. doi: 10.1016/j.cell.2022.03.039. Epub 2022 Apr 25.
20.6.946953.183894	183894	TALED_Left-ND1-AD-E1347A	TALED for ND1 mutation	Mammalian Expression	Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases. Cell. 2022 May 12;185(10):1764-1776.e12. doi: 10.1016/j.cell.2022.03.039. Epub 2022 Apr 25.
20.6.684916.137929	137929	pAAV-EFS-CjCas9-eGFP-HIF1a	CjCas9	AAV, CRISPR	In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni. Nat Commun. 2017 Feb 21;8:14500. doi: 10.1038/ncomms14500.
20.5.569538.78956	78956	pU6-As-crRNA		Mammalian Expression, CRISPR	Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nat Biotechnol. 2016 Jun 6. doi: 10.1038/nbt.3609.
20.4.822924.78957	78957	pU6-Lb-crRNA		Mammalian Expression, CRISPR	Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nat Biotechnol. 2016 Jun 6. doi: 10.1038/nbt.3609.
20.3.531239.104174	104174	pRG2		Mammalian Expression, CRISPR	Rescue of high-specificity Cas9 variants using sgRNAs with matched 5' nucleotides. Genome Biol. 2017 Nov 15;18(1):218. doi: 10.1186/s13059-017-1355-3.
20.1.405673.89508	89508	pET-Hisx6-rAPOBEC1-XTEN-nCas9-UGI-NLS	rAPOBEC1-nCas9 (D10A)-UGI-NLS	Bacterial Expression	Highly efficient RNA-guided base editing in mouse embryos. Nat Biotechnol. 2017 Feb 27. doi: 10.1038/nbt.3816.