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Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo.

To TL, Piggott BJ, Makhijani K, Yu D, Jan YN, Shu X
Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3338-43. doi: 10.1073/pnas.1502857112. Epub 2015 Mar 2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
64276pcDNA3.1 TEV (full-length)Expresses tobacco etch virus protease (TEV)
64277pcDNA3.1 iTEVExpresses infrared fluorescent tobacco etch virus protease sensor (iTEV)
64278pcDNA3.1 iCasper T2A HO1Expresses infrared fluorescent executioner caspase reporter (iCasper) plus human heme oxygenase 1

Antibodies from Article