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Human anti-varicella-zoster virus (VZV) recombinant monoclonal antibody produced after Zostavax immunization recognizes the gH/gL complex and neutralizes VZV infection.

Birlea M, Owens GP, Eshleman EM, Ritchie A, Traktinskiy I, Bos N, Seitz S, Azarkh Y, Mahalingam R, Gilden D, Cohrs RJ
J Virol. 2013 Jan;87(1):415-21. doi: 10.1128/JVI.02561-12. Epub 2012 Oct 17. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
64081VZV ORF 37(gH)eukaryotic expression plasmid for VZV glycoprotein H
64082VZV ORF 60 (gL)eukaryotic expression plasmid for VZV glycoprotein L

Antibodies from Article