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A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.

Okada N, Lin CP, Ribeiro MC, Biton A, Lai G, He X, Bu P, Vogel H, Jablons DM, Keller AC, Wilkinson JE, He B, Speed TP, He L
Genes Dev. 2014 Mar 1;28(5):438-50. doi: 10.1101/gad.233585.113. Epub 2014 Feb 14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
63932MSCV-miR-34aMSCV vector for overexpressing mouse miR-34
63933MSCV-miR-34b/34cMSCV vector for overexpressing mouse miR-34b/34c
64018Luc-Hdm4-3'UTR-F2d5Luciferase reporter of human Hdm4 3'UTR F2 fragment mutant #5

Antibodies from Article