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miR-34 miRNAs provide a barrier for somatic cell reprogramming.

Choi YJ, Lin CP, Ho JJ, He X, Okada N, Bu P, Zhong Y, Kim SY, Bennett MJ, Chen C, Ozturk A, Hicks GG, Hannon GJ, He L
Nat Cell Biol. 2011 Oct 23;13(11):1353-60. doi: 10.1038/ncb2366. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
63893Luc-Nanog-3'UTRLuciferase reporter of mouse wildtype Nanog 3'UTR
63894Luc-Nanog-3'UTRmutLuciferase reporter of mouse Nanog 3'UTR with the miR-34 target site mutated
63895Luc-Sox2-3'UTRLuciferase reporter of mouse wildtype Sox2 3'UTR

Antibodies from Article