Gcn5 and PCAF negatively regulate interferon-beta production through HAT-independent inhibition of TBK1.
Jin Q, Zhuang L, Lai B, Wang C, Li W, Dolan B, Lu Y, Wang Z, Zhao K, Peng W, Dent SY, Ge K
EMBO Rep. 2014 Nov;15(11):1192-201. doi: 10.15252/embr.201438990. Epub 2014 Sep 30.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
63705 | pMSCVpuro-PCAF | retroviral expression of human PCAF in mammalian cells |
63706 | pMSCVpuro-Gcn5 | retroviral expression of mouse Gcn5 in mammalian cells |
63707 | pMSCVpuro-Gcn5(D608A) | retroviral expression of enzyme-dead mouse Gcn5 in mammalian cells |
63708 | pMSCVpuro-F-Gcn5-NLSm | retroviral expression of cytoplasm-localized mouse Gcn5 in mammalian cells |