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Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow.

Zeng L, Zampetaki A, Margariti A, Pepe AE, Alam S, Martin D, Xiao Q, Wang W, Jin ZG, Cockerill G, Mori K, Li YS, Hu Y, Chien S, Xu Q
Proc Natl Acad Sci U S A. 2009 May 19;106(20):8326-31. doi: 10.1073/pnas.0903197106. Epub 2009 May 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
63677Ad-Flag-XBP1uAdenoviral vector for XBP1u expression
63678Ad-Flag-XBP1sAdenoviral vector for XBP1s expression
63679pShuttle-Flag-XBP1uAdenoviral shuttle vector for XBP1u expression
63680pCMV5-Flag-XBP1sMammalian expression of Flag tagged XBP1s

Antibodies from Article