The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.
Smit JJ, Monteferrario D, Noordermeer SM, van Dijk WJ, van der Reijden BA, Sixma TK
EMBO J. 2012 Oct 3;31(19):3833-44. doi: 10.1038/emboj.2012.217. Epub 2012 Aug 3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 63134 | pGEX6p1-GST-Rnf31 | Expression of human RNF31/HOIP codon optimized for E. coli and insect cells |
| 63135 | pGEX6p1-Rbck1 | Expression of human RBCK1/HOIL-1L |