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VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface.

Hesketh GG, Perez-Dorado I, Jackson LP, Wartosch L, Schafer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MN, Luzio JP, Owen DJ
Dev Cell. 2014 Jun 9;29(5):591-606. doi: 10.1016/j.devcel.2014.04.010. Epub 2014 May 22. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
62950VARP GFP-pLXINfull length human VARP with C-terminal EGFP tag cloned into pLXIN

Antibodies from Article