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CRL4(VprBP) E3 Ligase Promotes Monoubiquitylation and Chromatin Binding of TET Dioxygenases.

Nakagawa T, Lv L, Nakagawa M, Yu Y, Yu C, D'Alessio AC, Nakayama K, Fan HY, Chen X, Xiong Y
Mol Cell. 2015 Jan 22;57(2):247-60. doi: 10.1016/j.molcel.2014.12.002. Epub 2014 Dec 31. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
89735pcDNA3-FLAG-mTET2Expresses wildtype mouse TET2 in mammalian cells
89736pcDNA3-FLAG-mTET2 (CD)Expresses the CD-domain truncation to mouse TET2 in mammalian cells
89737pcDNA3-FLAG-mTET2 (N1041)Expresses the N1041 truncation to mouse TET2 in mammalian cells
89896pcDNA3-FLAG-mTET2 CD mutantExpresses mouse TET2 CD mutant in mammalian cells
89897pcDNA3-FLAG-mTET2 (N500)Expresses mouse TET2 N500 truncation in mammalian cells
133586pcDNA3-HA-VprBPExpresses human VprBP wildtype in mammalian cells
133587pcDNA3-HA-VprBP (RARA)Expresses human VprBP RARA mutant in mammalian cells
133588pcDNA3-HA-VprBP (N909)Expresses human VprBP N909 mutant in mammalian cells
133589pcDNA3-HA-VprBP (C590)Expresses human VprBP C590 mutant in mammalian cells

Antibodies from Article