A split-Cas9 architecture for inducible genome editing and transcription modulation.
Zetsche B, Volz SE, Zhang F
Nat Biotechnol. 2015 Feb 2. doi: 10.1038/nbt.3149.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 62883 | PX851 | N-term SpCas9 piece of inducible split-4 (Cas9(N)-FRB-NES split-4). |
| 62884 | PX852 | C-term SpCas9 piece of inducible split-4 (Cas9(C)-FKBP split-4). |
| 62885 | PX853 | N-term SpCas9 piece of inducible split-5 (Cas9(N)-FRB-NES split-5). |
| 62886 | PX854 | C-term SpCas9 piece of inducible split-5 (Cas9(C)-FKBP split-5). |
| 62887 | PX855 | N-term SpCas9 piece of inducible transcriptional activator (dCas9(N)-FRB-2xNES) |
| 62888 | PX856 | C-term SpCas9 piece of inducible transcriptional activator (dCas9(C)-FKBP-2xNLS-VP64) |
| 62889 | pLSC-5 | Lenti vector for expression of inducible split Cas9 |