Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
Gammage PA, Rorbach J, Vincent AI, Rebar EJ, Minczuk M
EMBO Mol Med. 2014 Apr;6(4):458-66. doi: 10.1002/emmm.201303672. Epub 2014 Feb 24.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
62798 | pcDNA3.1(-)_mtZFN(+)2G | mtZFN2G architecture bearing (+) FokI domain |
62799 | pcDNA3.1(-)_mtZFN(-)2G | mtZFN2G architecture bearing (-) FokI domain |