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Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.

Gammage PA, Rorbach J, Vincent AI, Rebar EJ, Minczuk M
EMBO Mol Med. 2014 Apr;6(4):458-66. doi: 10.1002/emmm.201303672. Epub 2014 Feb 24. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
62798pcDNA3.1(-)_mtZFN(+)2GmtZFN2G architecture bearing (+) FokI domain
62799pcDNA3.1(-)_mtZFN(-)2GmtZFN2G architecture bearing (-) FokI domain

Antibodies from Article