The duplicated alpha7 subunits assemble and form functional nicotinic receptors with the full-length alpha7.
Wang Y, Xiao C, Indersmitten T, Freedman R, Leonard S, Lester HA
J Biol Chem. 2014 Sep 19;289(38):26451-63. doi: 10.1074/jbc.M114.582858. Epub 2014 Jul 23.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 62276 | pcDNA3.1-CHRNA7 | mammalian expression of human Alpha7 (CHRNA7) |
| 62284 | pcDNA3.1-CHRFAM7A | mammalian expression of human duplicated Alpha7 (CHRFAM7A) |
| 62515 | pcDNA3.1-CHRFAM7ADelta2bp | mammalian expression of human duplicated Alpha7 with 2 bp deletion (CHRFAM7A-∆2bp) |
| 62629 | pcDNA3.1-CHRNA7-mGFP | mammalian expression of human Alpha7 (CHRNA7) with mEGFP fused into M3-M4 loop |
| 62630 | pcDNA3.1-CHRNA7-YFP | mammalian expression of human Alpha7 (CHRNA7) with YFP fused into M3-M4 loop |
| 62632 | pcDNA3.1-CHRNA7-mCherry | mammalian expression of human Alpha7 (CHRNA7) with mCherry fused into M3-M4 loop |
| 62633 | pcDNA3.1-CHRFAM7A-mGFP | mammalian expression of human duplicated Alpha7 (CHRFAM7A) with mEGFP fused into M3-M4 loop |
| 62634 | pcDNA3.1-CHRFAM7A-YFP | mammalian expression of human duplicated Alpha7 (CHRFAM7A) with YFP fused into M3-M4 loop |
| 62635 | pcDNA3.1-CHRFAM7A-mCherry | mammalian expression of human duplicated Alpha7 (CHRFAM7A) with mCherry fused into M3-M4 loop |
| 62636 | pcDNA3.1-CHRFAM7ADelta2bp-mGFP | mammalian expression of human duplicated Alpha7-2 bp deletion (CHRFAM7A-∆2bp) with mEGFP fused into M3-M4 loop |
| 62637 | pcDNA3.1-CHRFAM7ADelta2bp-YFP | mammalian expression of human duplicated Alpha7-2 bp deletion (CHRFAM7A-∆2bp) with YFP fused into M3-M4 loop |
| 62638 | pcDNA3.1-CHRFAM7ADelta2bp-mCherry | mammalian expression of human duplicated Alpha7-2 bp deletion (CHRFAM7A-∆2bp) with mCherry fused into M3-M4 loop |