High-throughput screening (HTS) and hit validation to identify small molecule inhibitors with activity against NS3/4A proteases from multiple hepatitis C virus genotypes.
Lee H, Zhu T, Patel K, Zhang YY, Truong L, Hevener KE, Gatuz JL, Subramanya G, Jeong HY, Uprichard SL, Johnson ME
PLoS One. 2013 Oct 9;8(10):e75144. doi: 10.1371/journal.pone.0075144. eCollection 2013.
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PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 61696 | pETDuet-1 Hepatitis C Virus NS3/NS4A | inducible dual expression of NS3 protease along with its cofactor NS4A |