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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin.

Keusekotten K, Elliott PR, Glockner L, Fiil BK, Damgaard RB, Kulathu Y, Wauer T, Hospenthal MK, Gyrd-Hansen M, Krappmann D, Hofmann K, Komander D
Cell. 2013 Jun 6;153(6):1312-26. doi: 10.1016/j.cell.2013.05.014. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
61464pOPINB-OTULIN (full-length, aa 1-352)Expresses human OTULIN (full-length) in E. coli.

Antibodies from Article