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The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis.

Guerrier S, Coutinho-Budd J, Sassa T, Gresset A, Jordan NV, Chen K, Jin WL, Frost A, Polleux F
Cell. 2009 Sep 4;138(5):990-1004. doi: 10.1016/j.cell.2009.06.047. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
61403pNeuroD-ires-GFPMammalian expression vector under the neuron-specific promoter NeuroD. Co-expression of GFP with IRES sequence
168501pCAG-SRGAP2A-EGFPExpression of full length SRGAP2 with a C-termonal EGFP fusion
168502pCAG-SRGAP2A-FBAR-mRFPExpression of the F-BAR domain (aa1-501) of SRGAP2 with a C-terminal mRFP fusion.

Antibodies from Article