An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.
Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ
Mol Cell. 2014 Aug 7;55(3):436-50. doi: 10.1016/j.molcel.2014.06.021. Epub 2014 Jul 17.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 61210 | pENTR-FLAG-hDIXDC1-L-WT | Entry clone encoding long isoform of human DIXDC1 |
| 61211 | pENTR-FLAG-hDIXDC1-L-S592A | Entry clone encoding long isoform of human DIXDC1 |
| 61212 | pENTR-FLAG-hDIXDC1-L-F630S | Entry clone encoding long isoform of human DIXDC1 |
| 61213 | pBabe-Hygro-FLAG-hDIXDC1 WT | Retrovirus expressing long isoform of human DIXDC1 |
| 61214 | pBabe-Hygro-FLAG-hDIXDC1 S592A | Retrovirus expressing long isoform of human DIXDC1 |
| 61215 | pBabe-Hygro-GFP | Retrovirus expressing GFP |
| 61216 | pDONR-mDIXDC1 WT | Entry clone encoding long isoform of mouse DIXDC1 |
| 61218 | pLenti-CMV/TO-Puro-FLAG-hDIXDC1 WT | Lentivirus expressing long isoform of human DIXDC1 |
| 61219 | pLenti-CMV/TO-Puro-FLAG-hDIXDC1 S592A | Lentivirus expressing long isoform of human DIXDC1 |
| 61220 | pLenti-PGK-Blast-FLAG-hDIXDC1 WT | Lentivirus expressing long isoform of human DIXDC1 |
| 61221 | pLenti-PGK-Blast-FLAG-hDIXDC1 S592A | Lentivirus expressing long isoform of human DIXDC1 |
| 61222 | pcDNA3-FLAG-hDIXDC1 WT | Mammalian expression vector encoding long isoform of human DIXDC1 |
| 61223 | pcDNA3-FLAG-hDIXDC1 S592A | Mammalian expression vector encoding long isoform of human DIXDC1 |
| 61224 | pQCXIB-FLAG-hDIXDC1-L-WT | Retrovirus expressing long isoform of human DIXDC1 |
| 61225 | pQCXIB-FLAG-hDIXDC1-L-S592A | Retrovirus expressing long isoform of human DIXDC1 |
| 61230 | pLentiX2-PURO-shGFP | Lentivirus expressing shRNA to GFP |
| 61231 | pLentiX2-PURO-shLKB1-Ms | Lentivirus expressing shRNA to mouse LKB1 |
| 61232 | pLentiX2-PURO-shDIXDC1-Ms-57 | Lentivirus expressing shRNA to mouse DIXDC1 |
| 61233 | pLentiX2-PURO-shDIXDC1-Ms-58 | Lentivirus expressing shRNA to mouse DIXDC1 |
| 61234 | pENTR-TER+-shLKB1-Ms | Entry clone encoding shRNA to mouse LKB1 |
| 61235 | pENTR-TER+-shDIXDC1-Ms-57 | Entry clone encoding shRNA to mouse DIXDC1 |
| 61236 | pENTR-TER+-shDIXDC1-Ms-58 | Entry clone encoding shRNA to mouse DIXDC1 |
| 61237 | pENTR-TER+-shDIXDC1-Hu-16 | Entry clone encoding shRNA to human DIXDC1 |
| 61239 | pENTR-MYC-hDIXDC1-L-WT | Entry clone encoding long isoform of human DIXDC1 |
| 61240 | pENTR-MYC-hDIXDC1-L-S592A | Entry clone encoding long isoform of human DIXDC1 |
| 61241 | pENTR-MYC-hDIXDC1-L-F630S | Entry clone encoding long isoform of human DIXDC1 |
| 61242 | pLentiX2-PURO-shLKB1-Hu | Lentivirus expressing shRNA to human LKB1 |
| 61243 | pENTR-TER+-shLKB1-Hu | Entry clone encoding shRNA to human LKB1 |